estimate_gfr_ckdepi: Estimate creatinine clearance and glomerular filtration rate...
In LS31/clinicalr: Clinical calculations

Description Usage Arguments Value Caveats References See Also

The CKD-EPI formula is calculated in two stages. First, Z = \frac{\text{creatinine}}{κ}, where κ is 61.9 for females and 79.6 for males. Then, if Z < 1, use 141 \times Z^(α) \times 1^{-1.209} \times 0.993^{\text{age}} \times S \times A, where α is -0.329 in females and -0.411 in males, S is 1.018 in females and 1 in males, and A is 1.159 for African-Americans and 1 for non-African-Americans. However, if Z > 1, use 141 \times 1^{α} \times Z^{-1.209} \times 0.993^{\text{age}} \times S \times A, where α is -0.329 in females and -0.411 in males, S is 1.018 in females and 1 in males, and A is 1.159 for African-Americans and 1 for non-African-Americans.

1	estimate_gfr_ckdepi(creatinine, age, is_female, is_african_american)

`creatinine`	Creatinine (\text{μmol} \text{l}^{-1}).
`age`	Age (years).
`is_female`	`TRUE` if patient is female, `FALSE` if patient is male.
`is_african_american`	`TRUE` if patient is African-American, `FALSE` if patient is not.

eGFR (\text{ml} \text{min}^{-1} 1.73 \text{m}^{-2}), or NA if any parameters are NA.

This is the formula for when cystatine C values are unavailable. The factor 'African-American' was published as black/non-black. I do not know if this is an acceptable/usable generalisation for all people with a black skin tone (or for people of other non-Caucasian, non-African-American descent for that matter).

Levey, A. S. et al. A New Equation to Estimate Glomerular Filtration Rate. Ann Intern Med 150, 604 (2009).

units::set_units(), units::drop_units()

LS31/clinicalr documentation built on Nov. 16, 2020, 7:58 p.m.