Description Usage Arguments Details Value
stage_two
computes the functions c_2 and n_2 that hold the error constraints and are optimal w.r.t.
expected sample size under the alternative for a prespecified first stage.
1 | stage_two(parameters, cf, ce, n1)
|
parameters |
Parameters specifying the design |
cf |
Boundary for stopping for futility |
ce |
Boundary for stopping for efficacy |
n1 |
First stage sample size |
stage_two
is the base of direct_design_smooth.
A vector. The first half give the c_2, and the second the n_2-values, on a equidistance grid inside the interval (cf,ce).
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