NEWS.md

In Merck/metalite.ae: Adverse Events Analysis Using 'metalite'

metalite.ae 0.1.3

New features

• format_ae_specific() now has new arguments filter_method and filter_criteria to control displayed rows in a table, sort_order and sort_column to sort an output table, and hide_soc_stats to control display of statistics for SOC rows (#191, #192, #203).
• Add data/metalite_ae_adesxum.rda (#189).
• Add event counts to avg_count() and extend_ae_specific_events() (#194).
• Add empty_table() to return an empty table object when data has no population (#200).

Bug fixes

• Fix bug to correctly display the order of means of duration and means of event count in extend_ae_specific_events() and extend_ae_specific_duration()(#194, #199).
• Fix bug to avoid an error when a treatment group has no observation to calculate event counts and duration in avg_event() and avg_duration() (#199).
• Fix bug to avoid an error when there is no observation to summarize event counts and duration in avg_event(), avg_duration(), extend_ae_specific_events() and extend_ae_specific_duration() (#200).

Improvements

• Update fmt_est() to change display of missing values from a character string of "NA" to a blank in an output table (#194).
• Update extend_ae_specific_inference() to pass additional arguments to rate_compare_sum() (#197).

metalite.ae 0.1.2

New features

• tlf_ae_summary() now has a new argument title for a user-customized title (#133).
• Add new functions: extend_ae_specific_subgroup(), prepare_ae_specific_subgroup(), format_ae_specific_subgroup(), tlf_ae_specific_subgroup(), extend_ae_summary_eaer(), format_ae_exp_adj() and tlf_ae_exp_adj() (#150, #161, #174, #180).
• Add data/metalite_ae_adex.rda (#164).
• Add new vignettes: vignette("ae-specific-subgroup") and vignette("exposure-adjusted-event-rate") (#167, #169).
• Add System Organ Classes (SOC) information to outdata in prepare_ae_specific() (#186).

Bug fixes

• Fix bug to avoid warning messages when no comparison variables are requested in format_ae_specific() (#135).
• Fix bug to align the row order of output data with the input one in avg_event() and avg_duration() (#136).
• Fix bug to check missing grouping variable after a subset of input data in prepare_ae_specific() (#137).
• Fix bug to display item if AE term has NA in prepare_ae_specific() (#166).
• Fix bug to correctly assign treatment labels when a treatment variable has NA (#179).

Improvements

• Update GitHub Actions workflow (#131, #163, #181).
• Add styler workflow (#134).
• Add CRAN download badge (#140).
• Remove dependencies on dplyr and tidyr from avg_event(), avg_duration() and fmt_val() (#136).
• Change the default value of the title argument in tlf_ae_specific() (#138).
• Remove R/n_subject.R and change to use metalite::n_subject() in prepare_ae_specific() (#144).
• Race values for adsl and adae are converted to title case in meta_ae_exmple() (#158).
• Organize files for utility functions (#159)
  • Rename R/rtf_output.R to R/utility.R.
  • Remove rate_compare_sum.R, R/to_mock.R and R/to_sentence.R.
  • Move to_rate_compare_sum() to R/rate_compare.R, and move to_mock() and to_sentence() to R/utility.R.
• Remove library calls from tests (#183).
• Add R/outdata.R to control outdata object (#161).
• Add an installation section to README.md (#177).
• Improve style and formatting for vignettes and code (#158, #168).

metalite.ae 0.1.1

• Updated the DESCRIPTION file to reformat the reference.
• Uncommented the previously commented code example.

metalite.ae 0.1.0

• Initial submission to CRAN.
• Added a NEWS.md file to track changes to the package.

Merck/metalite.ae documentation built on Feb. 10, 2025, 5:03 p.m.