runSimulationStudy: Runs Simulation Study

In OHDSI/PropensityScoreEvaluation: Propensity Score Evluation

Description

This function runs a simulation to compare LASSO, exposure based hdps, and bias based hdps as propensity score methods

Usage

runSimulationStudy(simulationProfile, simulationSetup, cohortMethodData,
  simulationRuns = 10, trueEffectSize = NA, outcomePrevalence = NA,
  hdpsFeatures, stratify = FALSE, discrete = FALSE,
  ignoreCensoring = FALSE, fudge = 0.001, psPrior = NULL, maxRatio = 1,
  numStrata = 10, useCovariates = FALSE)

Arguments

simulationProfile	simulationProfile object created by createCMDSimulationProfile function
simulationRuns	Number of simulations to run (1 simulation = reroll outcomes)
trueEffectSize	True effect size for exposure to simulate. If set to NULL keeps observed effect size from simulation profile
outcomePrevalence	Outcome prevalence to simulate; adjusts outcome baseline survival function to achieve. If null keeps observed
hdpsFeatures	TRUE = using HDPS features; FALSE = using FeatureExtraction features
ignoreCensoring	Ignore censoring altogether; sets censoring process baseline survival function to 1
studyPop	Study population created by createStudyPopulation function
confoundingScheme	Type of unmeasured confounding to use for PS (0 = none; 1 = demographics; 2 = random proportion; 3 = demographics and random proportion)
confoundingProportion	Proportion of covariates to hide from propensity score as unmeasured confounding
ignoreCensoringCovariates	Ignore covariates effects on censoring process; only uses baseline function
threads	Number of parallel threads to use

Value

Returns the following:

trueOutcomeModel

the non-exposure oefficients used in the outcome generating model

trueEffectSize

coefficient for exposure effect

estimatesLasso

logRr, bound, and sd for LASSO estimate for each simulation

estimatesExpHdps

logRr, bound, and sd for exposure based hdps

estimatesBiasHdps

logRr, bound, and sd for bias based hdps

aucLasso

auc for LASSO propensity score

aucExpHdps

auc for exposure based hdps propensity score

aucBiasHdps

auc for bias based hdps propensity score

psLasso

propensity scores for subjects in study population for LASSO

psExp

propensity scores for subjects in study population for exposure based hdps

psBias

propensity scores for subjects in study population for bias based hdps; propensity and preference scores are averaged over simulation runs

outcomePrevalence

outcome prevalence of simulation

OHDSI/PropensityScoreEvaluation documentation built on May 12, 2019, 8:38 a.m.