Description Usage Arguments Value
This function is designed to estimate the reference ratio in the absence of any regulatory difference; that is, the reference bias due to alignment. This is done by obtaining the median ratio between eh1 and eh2 across the top 20
1 | get_r0(ASEdat, eh1 = "refCount", eh2 = "altCount")
|
ASEdat |
Dataframe containing reference and alternative count data. |
eh1 |
A string with the column name of the reference count data |
eh2 |
A string with the column name of the alternative count data |
A numeric estimate of the reference bias r0 for the given library.
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