mwlsr.contrastTest: mwlsr.contrastTest

In PfaffLab/mwlsr: Multiple Weighted Least Squares Regression

Description

Contrast one or more levels of the design factors against one or more other levels. This kind of test uses the full model's dispersions as a basis for the comparison of the means of two conditions. Useful for comparing levels of a single multi-level factor, such as different groups in an RNA-Seq experiment, to one another to check for statistical difference in means.

Usage

mwlsr.contrastTest(fit, contrast = NULL, coef = NULL, ncomps = NULL,
  squeeze.var = FALSE)

Arguments

fit	mwlsr fit object
contrast	Single-column contrast matrix
coef	Coefficient to test (for intercept models)
ncomps	Sidak post-hoc correction factor. Default behavior is no correction.
squeeze.var	Employ limma's 'squeeze.var' method which not only adjusts the model's dispersion but also the residual degrees of freedom

Value

data.frame with results of the test

PfaffLab/mwlsr documentation built on May 12, 2019, 5:22 p.m.