README.md
In Qiaolan/MTAFS: An Adaptive and Robust Method for Multi-trait Analysis of Genome-wide Association Studies Using Summary Statistics
MTAFS: An Adaptive and Robust Method for Multi-trait Analysis of Genome-wide Association Studies Using Summary Statistics
MTAFS is an efficient and robust method for multi-trait analysis of GWAS. It uses GWAS summary statistics and construct its test statistic adaptively. Compared with many existing methods, MTAFS has three compelling features making it a useful method in practice:
- MTAFS can control type 1 error well even when there are hundreds of traits and significance levels are small.
- MTAFS has robust power performance given various settings.
- MTAFS is an efficient method by avoiding permutations.
Installation
devtools::install_github("Qiaolan/MTAFS") or remotes::install_github("Qiaolan/MTAFS")
library(MTAFS)
Vignette
The vignette of MTAFS is here
Qiaolan/MTAFS documentation built on Feb. 26, 2023, 7:02 p.m.
R Package Documentation
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We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
MTAFS: An Adaptive and Robust Method for Multi-trait Analysis of Genome-wide Association Studies Using Summary Statistics
MTAFS is an efficient and robust method for multi-trait analysis of GWAS. It uses GWAS summary statistics and construct its test statistic adaptively. Compared with many existing methods, MTAFS has three compelling features making it a useful method in practice:
- MTAFS can control type 1 error well even when there are hundreds of traits and significance levels are small.
- MTAFS has robust power performance given various settings.
- MTAFS is an efficient method by avoiding permutations.
Installation
devtools::install_github("Qiaolan/MTAFS") or remotes::install_github("Qiaolan/MTAFS")
library(MTAFS)
Vignette
The vignette of MTAFS is here
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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