README.md

In RemyNicolle/CoRegNet-bioc: CoRegNet : reconstruction and integrated analysis of co-regulatory networks

CoRegNet

CoRegNet is an R/Bioconductor package for gene regulatory network inference and analysis.

It uses a a Shiny/Cytoscape.js interface for the analysis of networks.

Install

From R :

source("http://bioconductor.org/biocLite.R")
biocLite("CoRegNet")

Quick user guide

1. reconsruct a large-scale regulatory network from a gene expression matrix EXP

GRN = hLICORN(EXP)

1. Infer transcription factor activity

influence = regulatorInfluence(GRN,EXP)

1. Retrieve inferred co-coregulators

coregs= coregulators(GRN,EXP)

1. Analyze the network of cooperative regulators using an interactive display display(GRN,EXP,influence)

RemyNicolle/CoRegNet-bioc documentation built on Dec. 18, 2021, 9:57 a.m.