derive_param_extreme_record: Adds a Parameter Based on First or Last Record from Multiple...

In Roche-GSK/admiral: ADaM in R Asset Library

Adds a Parameter Based on First or Last Record from Multiple Sources

Description

The derive_param_extreme_record() function has been deprecated in favor of derive_extreme_event().

Generates parameter based on the first or last observation from multiple source datasets, based on user-defined filter, order and by group criteria. All variables of the selected observation are kept.

Usage

derive_param_extreme_record(
  dataset = NULL,
  sources,
  source_datasets,
  by_vars = NULL,
  order,
  mode,
  set_values_to
)

Arguments

dataset	Input dataset Default value NULL
sources	Sources A list of records_source() objects is expected. Default value none
source_datasets	Source datasets A named list of datasets is expected. The dataset_name field of records_source() refers to the dataset provided in the list. The variables specified by the order and the by_vars arguments are expected after applying new_vars. Default value none
by_vars	Grouping variables If the argument is specified, for each by group the observations are selected separately. Default value NULL
order	Sort order If the argument is set to a non-null value, for each by group the first or last observation from the source datasets is selected with respect to the specified order. Variables created via new_vars e.g., imputed date variables, can be specified as well (see examples below). Please note that NA is considered as the last value. I.e., if a order variable is NA and mode = "last", this observation is chosen while for mode = "first" the observation is chosen only if there are no observations where the variable is not NA. Permitted values list of expressions created by exprs(), e.g., exprs(ADT, desc(AVAL)) Default value none
mode	Selection mode (first or last) If "first" is specified, for each by group the first observation with respect to order is included in the output dataset. If "last" is specified, the last observation is included in the output dataset. Permitted values "first", "last" Default value none
set_values_to	Variables to be set The specified variables are set to the specified values for the new observations. A list of variable name-value pairs is expected. LHS refers to a variable. RHS refers to the values to set to the variable. This can be a string, a symbol, a numeric value or NA, e.g., exprs(PARAMCD = "PD", PARAM = "First Progressive Disease"). Default value none

Details

The following steps are performed to create the output dataset:

1. For each source dataset the observations as specified by the filter element are selected.

2. Variables specified by new_vars are created for each source dataset.

3. The first or last observation (with respect to the order variable) for each by group (specified by by_vars) from multiple sources is selected and added to the input dataset.

Value

The input dataset with the first or last observation of each by group added as new observations.

See Also

Other deprecated: date_source(), derive_var_dthcaus(), derive_var_extreme_dt(), derive_var_extreme_dtm(), dthcaus_source(), get_summary_records()

Examples

aevent_samp <- tibble::tribble(
  ~USUBJID, ~PARAMCD,                       ~PARAM,     ~RSSTDTC,
  "1",          "PD",  "First Progressive Disease", "2022-04-01",
  "2",          "PD",  "First Progressive Disease", "2021-04-01",
  "3",          "PD",  "First Progressive Disease", "2023-04-01"
)

cm <- tibble::tribble(
  ~STUDYID, ~USUBJID, ~CMDECOD,     ~CMSTDTC,
  "1001",        "1",    "ACT", "2021-12-25"
)

pr <- tibble::tribble(
  ~STUDYID, ~USUBJID, ~PRDECOD,     ~PRSTDTC,
  "1001",        "1",    "ACS", "2021-12-27",
  "1001",        "2",    "ACS", "2020-12-25",
  "1001",        "3",    "ACS", "2022-12-25",
)
derive_param_extreme_record(
  dataset = aevent_samp,
  sources = list(
    records_source(
      dataset_name = "cm",
      filter = CMDECOD == "ACT",
      new_vars = exprs(
        ADT = convert_dtc_to_dt(CMSTDTC),
        AVALC = CMDECOD
      )
    ),
    records_source(
      dataset_name = "pr",
      filter = PRDECOD == "ACS",
      new_vars = exprs(
        ADT = convert_dtc_to_dt(PRSTDTC),
        AVALC = PRDECOD
      )
    )
  ),
  source_datasets = list(cm = cm, pr = pr),
  by_vars = exprs(USUBJID),
  order = exprs(ADT),
  mode = "first",
  set_values_to = exprs(
    PARAMCD = "FIRSTACT",
    PARAM = "First Anti-Cancer Therapy"
  )
)

Roche-GSK/admiral documentation built on April 14, 2025, 12:36 p.m.