filter_donors: Choose most informative donors for imputation

In ShamamW/PHCPImpute: PHCP-BASED IMPUTATION

Choose most informative donors for imputation

Description

The donors are chosen based on K. Wasik et al, 2021 This function is used as a nested function in phcp_impute()

Usage

filter_donors(data, n_donors, n_info, freq)

Arguments

data	the input file that was generated with input
n_donors	the number of donors' haplotypes to choose
n_info	the number of columns in the data file before the columns of the haplotypes
freq	the maximal minor allele frequency in variants to consider when choosing the donors

Value

the data file with the chosen haplotypes

References

K. Wasik et al., Comparing low-pass sequencing and genotyping for trait mapping in pharmacogenetics. BMC genomics 22, 197 (2021).

See Also

phcp_impute which is the imputation function that uses this function

input that generates the data input for this function

ShamamW/PHCPImpute documentation built on Oct. 26, 2022, 6:34 a.m.