Shamir-Lab/PRODIGY: Personalized prioritization of driver genes

PRODIGY analyzes the expression and SNV profiles of a patient along with data on known pathways and protein-protein interactions. PRODIGY quantifies the impact of each mutated gene on every transcriptionally deregulated pathway using the prize collecting Steiner tree model. Mutated genes are ranked by their aggregated impact on all deregulated pathways.

Getting started

Package details

MaintainerGal Dinstag <galdinstag@mail.tau.ac.il>
LicenseGPL
Version1.0
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("Shamir-Lab/PRODIGY")
Shamir-Lab/PRODIGY documentation built on March 27, 2022, 5:29 p.m.