SharonLutz/pleiotropy: This Package Tests For Pleiotropy

This package provides two approaches to formally test for pleiotropy with a single SNP (pleiotropySNP) or a region (pleiotropyGENE). These approaches depend on permuting the phenotypes of interest and comparing the set of observed p-values to the set of permuted p-values in relation to the origin (e.g. a vector of zeros) either using the Hausdorff metric or a cut-off based approach.

install.packages("remotes")
remotes::install_github("SharonLutz/pleiotropy")