pleiotropy-package: This Package Tests For Pleiotropy

pleiotropy-packageR Documentation

This Package Tests For Pleiotropy

Description

This package provides two approaches to formally test for pleiotropy with a single SNP (pleiotropySNP) or a region (pleiotropyGENE). These approaches depend on permuting the phenotypes of interest and comparing the set of observed p-values to the set of permuted p-values in relation to the origin (e.g. a vector of zeros) either using the Hausdorff metric or a cut-off based approach.

Author(s)

Sharon Lutz, Annie Thwing

Maintainer: Annie Thwing <annie.thwing@ucdenver.edu>

References

Lutz SM, Fingerlin T, John E Hokanson, Lange C. (2016) A General Approach to Testing for Pleiotropy with Rare and Common Variants. (Submitted Manuscript).


SharonLutz/pleiotropy documentation built on Jan. 4, 2024, 7:51 a.m.