plot_lrr_maf: CNV raw data plot

Description Usage Arguments Details Value Author(s)

View source: R/plot_lrr_maf.R

Description

lrr_plot create scatter plots of LRR and MAF in a selected region

Usage

1
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plot_lrr_maf(chr, cnv.start, cnv.end, region = 5, final.rep,
  window = 100, step = 50)

Arguments

chr

Chromosome where the putative CNV is present (e.g "1", not "chr1")

cnv.start

Start position of the CNV

cnv.end

End position of the CNV

region

Size of the region to be plotted on each side of the CNV

final.rep

Data frame in Illumina Final report format

window

Sliding window size (in SNPs)

step

Sliding window step (in SNPs)

Details

This function can be used to inspect the raw data (LRR and MAF) of putative CNV calls. It also calculate the mean LRR in a sliding window with default size of 100 SNPs and default step of 50 SNPs. A bar in each plot indicate the position of the call. \newline For convenience consider to select the data from the entire FinalREport outside R, e.g. using awk. As an example, awk -F"\t" '{if ($1 == "sampleID" && $3 == 1) print $0}' FinalReport.txt > chr1_sampleID.tsv will select the SNPs in chromosome 1 of a desired sample and save it as a separate file that can be more easily loaded in R. \newline In any case final.rep must be a data-frame containing the data of one single sample and the following columns: "Chr", "Position", "Log.R.Ratio", "B.allele.Freq". Order is not relevant.

Value

pl

Author(s)

Simone Montalbano simone.montalbano@protonmail.com


SinomeM/cnv_geaRs documentation built on Dec. 4, 2020, 3:06 a.m.