nca.check.sim: Check simulated data

In UUPharmacometrics/ncappc: NCA Calculations and Population Model Diagnosis

Check simulated data

Description

nca.check.sim Checks simulated data for compatibility with ncappc and processes the data with various filtering criteria.

Usage

nca.check.sim(
  simData,
  idNmSim = "ID",
  timeNmSim = "TIME",
  concNmSim = "DV",
  filterNm = NULL,
  filterExcl = NULL,
  str1Nm = NULL,
  str1 = NULL,
  str2Nm = NULL,
  str2 = NULL,
  str3Nm = NULL,
  str3 = NULL,
  adminType = "extravascular",
  TI = NULL,
  doseAmtNm = NULL,
  blqNm = NULL,
  blqExcl = 1,
  evid = TRUE,
  evidIncl = 0,
  mdv = FALSE
)

Arguments

simData	Simulated concentration-time data.
idNmSim	Column name for ID in simulated data. Default is "ID"
timeNmSim	Column name for time in simulated data. Default is "TIME"
concNmSim	Column name for concentration in simulated data. Default is "DV"
filterNm	Column name to filter data. Default is NULL
filterExcl	Row exclusion criteria based on the column defined by filterNm. This can be numeric value or logical condition (e.g. c(1, 2, "<20", ">=100", "!=100")). Default is NULL
str1Nm	Column name for 1st level population stratifier. Default is NULL
str1	Stratification ID of the members within 1st level stratification (e.g c(1,2)). Default is NULL
str2Nm	Column name for 2nd level population stratifier. Default is NULL
str2	Stratification ID of the members within 2nd level stratification (e.g c(1,2)). Default is NULL
str3Nm	Column name for 3rd level population stratifier. Default is NULL
str3	Stratification ID of the members within 3rd level stratification (e.g c(1,2)). Default is NULL
adminType	Route of administration. Allowed options are iv-bolus, iv-infusion or extravascular. Default is "extravascular"
TI	Infusion duration. If TI is a single numeric value, TI is the same for all individuals. If TI is the name of a column with numeric data present in the data set, TI is set to the unique value of the column for a given individual. Default is NULL
doseAmtNm	Column name to specify dose amount. Default is NULL
blqNm	Name of BLQ column if used to exclude data. Default is NULL
blqExcl	Excluded BLQ value; either a numeric value or a logical condition (e.g. 1 or ">=1" or c(1,">3")). Used only if the blqNm is not NULL. Default is "1"
evid	If TRUE EVID is used to filter data. Default is TRUE
evidIncl	Included values in EVID. Default is "0"
mdv	If TRUE MDV is used to include data when MDV=0. Default is FALSE

Details

nca.check.sim Checks simulated data for compatibility with ncappc.

Value

A list of objects

UUPharmacometrics/ncappc documentation built on March 23, 2022, 8:59 a.m.