binsearchtol | binary search with arbitrary resolution |
buildTrial | Generate efficacy boundaries and then calculate trial... |
buildTrial_Maurer_Bretz_2013 | Generate efficacy boundaries and then calculate trial... |
cleanArgList | Clean a list of arguments (for internal use) |
feasibility_check | Check feasibility of power constraints |
getBoundsFromOptimSoln | Get efficacy boundary from a solution found by... |
get_case_perf_obj | Get trial performance for each case. |
getEffBounds | Compute efficacy stopping boundaries for an adaptive... |
get_E_SS | Returns the expected sample size (mostly for internal use) |
getExampleInputsMISTIE | Example inputs for 'optimizeTrial' |
get_perf_mat | Get matrix with trial design performance in each supplied... |
getSmoothBounds | Get smooth parametric boundaries for efficacy and futility |
min_E_SS_power_constraints | Sample objective function to minimize |
min_n_multistage | Find the smallest total sample size such that a multi-stage... |
optimizeTrial | Use simulated annealing to search over a space of trial... |
sann_random | A simulated annealing variant that re-evaluates the reference... |
simTrial | Simulate a trial to compute power, expected sample size, and... |
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