inst/shiny/www/nucleosomesDescription.md
In adeschen/nucleoSimShiny: Interactive Generator of Nucleosomes Maps
A nucleosome consisting of a segment of DNA wound around eight
histone proteins. It forms a structure of approximately 147 base pairs of
DNA.
The positions of nucleosomes control local DNA accessibility. Thus, nucleosomes
play a critical role in regulating the process of gene transcription.
Several software, such as NORMAL (Polishko et al, 2012) and PING
(Woo et al, 2013), have been developed to detect the position of
the nucleosomes on the genome using paired-end reads. Synthetically generated
nucleosome maps are useful tools to test the sensitivity and the accurancy of
those software.
This application enables the generation ofsynthetic nucleosome maps through an
interactive interface.
The recommended procedure:
Set the parameters in the Parameters panel.
Visualize the nucleosome map in the Graph panel.
* Download dataset in the Download panel.
adeschen/nucleoSimShiny documentation built on May 10, 2019, 5:53 a.m.
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A nucleosome consisting of a segment of DNA wound around eight histone proteins. It forms a structure of approximately 147 base pairs of DNA.
The positions of nucleosomes control local DNA accessibility. Thus, nucleosomes play a critical role in regulating the process of gene transcription.
Several software, such as NORMAL (Polishko et al, 2012) and PING (Woo et al, 2013), have been developed to detect the position of the nucleosomes on the genome using paired-end reads. Synthetically generated nucleosome maps are useful tools to test the sensitivity and the accurancy of those software.
This application enables the generation ofsynthetic nucleosome maps through an interactive interface.
The recommended procedure: Set the parameters in the Parameters panel. Visualize the nucleosome map in the Graph panel. * Download dataset in the Download panel.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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