README.md

In aj-grant/mrcovreg: Package for an efficient and robust approach to Mendelian randomization with measured pleiotropic effects

mr_covreg

An R package which implements a method for estimation of a causal effect in a Mendelian randomization setting as described in

Grant, A.J. and Burgess, S. (2020). An efficient and robust approach to Mendelian randomization with measured pleiotropic effects in a high-dimensional setting. Biostatistics, https://doi.org/10.1093/biostatistics/kxaa045

Installation

library(devtools)
install_github("aj-grant/mvcovreg")

Docker

docker build -t mrcovreg:latest .
docker run -it mrcovreg R

Applied example

The file Urate_CHD_script.R in the example folder replicates the applied example in the paper.

Simulations

The simulations folder contains R scripts to replicate the simulations presented in the paper.

aj-grant/mrcovreg documentation built on Nov. 25, 2020, 12:14 p.m.