iv_free: IV-free exposure

In amymariemason/SUMnlmr: Non-Linear Mendelian Randomization On Partially Summarized Data

IV-free exposure

Description

iv_free computes the IV-free exposure.

Usage

iv_free(y, x, g, covar = NULL, q = 10, family = "gaussian", controlsonly = T)

Arguments

y	vector of outcome values.
x	vector of exposure values.
g	the instrumental variable.
covar	a matrix of covariates.
q	the number of quantiles the exposure distribution is to be split into. The default is deciles (i.e. 10 quantiles).
family	a description of the error distribution and link function to be used in the model (either "gaussian" or "binomial" can be specified).
controlsonly	whether to estimate the gx association in all people, or in controls only. This is set to TRUE by default, but has no effect if family is gaussian.

Value

xcoef	the association between the exposure and the instrument
x0	the IV-free exposure.
x0q	the quantiles of x0.

Author(s)

Amy Mason [e-mail] based on similar function in nlmr by James R Staley

amymariemason/SUMnlmr documentation built on July 22, 2024, 10:03 a.m.