ArrangeData | Data trimming |
CenterData | Data centering |
CheckArguments_Impute | Argument check to Impute() |
ChooseMethod | Method choice per gene |
Combine | Combine imputation methods |
ComputeMSEGenewise | Computation of MSE per gene |
CreateArgCheck | Argument check |
CreateTrainData | Preparation of training data for method evaluation |
DataCheck_Matrix | Data check (matrix) |
DataCheck_Network | Data check (network) |
DataCheck_SingleCellExperiment | Data check (SingleCellExperiment) |
DataCheck_TrLength | Data check (transcript length) |
demo_data | Small dataset for example purposes |
demo_net | Small regulatory network for example purposes |
demo_sce | Small dataset for example purposes |
EvaluateMethods | Imputation method evaluation on training set |
GetDropoutProbabilities | Get dropout probabilities |
HandleBiologicalZeros | Get dropout probabilities |
Impute | Dropout imputation using different methods |
ImputeBaseline | Impute using average expression across all cells |
ImputeDrImpute | Use DrImpute |
ImputeNetParallel | Network-based parallel imputation |
ImputeNetwork | Network-based imputation |
ImputeNPDropouts | Helper function to PseudoInverseSolution_percell |
ImputePredictiveDropouts | Helper function to PseudoInverseSolution_percell |
ImputeSAVER | Use SAVER |
MaskData | Masking of entries for performance evaluation |
MaskerPerGene | Helper mask function |
network.coefficients | Transcriptome wide gene regulatory network |
NormalizeRPM | RPM normalization |
NormalizeTPM | TPM normalization |
PseudoInverseSolution_percell | Network-based parallel imputation - Moore-Penrose... |
ReadData | Data read |
ReturnChoice | Wrapper for return of EvaluateMethods() |
ReturnOut | Wrapper for return of Impute() |
SetBiologicalZeros | Set biological zeros |
SplitData | Selection of samples for training |
transcript_length | Table for transcript length calculations |
WriteCSV | Write csv file |
WriteTXT | Write txt file |
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