andreyshabalin/simPRS: Fast Simulation of Polygenic Risk Scores
Simulation of Polygenic Risk Score calculations allows to (1) Select an optimal p-value threshold, (2) Perform power analyses, and (3) Estimate polygenicity of a phenotype. Simulations are performed without direct simulations of the genotype and phenotype data. Instead, genome-wide association study (GWAS) summary statistics are generated directly from their finite sample distributions.
Getting started
Browse package contents
Package details |
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| Maintainer | |
| License | LGPL-3 |
| Version | 0.9 |
| URL | https://github.com/andreyshabalin/simPRS https://andreyshabalin.shinyapps.io/simPRS/ |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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