dafsFilter: dafsFilter Function to filter expression data within an "se"...

Description Usage Arguments Details Value Author(s) References Examples

Description

This function filters the expression of the supplied "se" object, by invoking the dafsFilter (dafs) function. dafsFilter is a filtering function used to remove rows (genes) of various expression data.

Usage

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Arguments

se

A SummExp object.

PLOT

Boolean, toggles plotting.

Details

This function filters the expression of the supplied se object using a Data Adaptive Flag filter. The internal function uses a vector to store Kolmogorov Smirnov distance statistics, loops through cuts of the data to determine targeted K-S statistic, selects data greater than a quantile and runs Mclust on that data to determine theoretical distribution. The wrapper uses simpleFilter to determine first left-most local minima (using the Earth library).

Value

Returns an invisible, filtered SummExp object.

Author(s)

AJ Vaestermark, JR Walters.

References

BMC Bioinformatics, 2014, 15:92

Examples

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library(mclust)
library(edgeR)
data(hmel.se)
f_se <- dafsFilter(se)

avastermark19/doseR_0.99.8 documentation built on May 6, 2019, 12:09 p.m.