lee.pwr: Compute power for SKAT (given chi-square mixture parameters)...

Description Usage Arguments Value References

View source: R/sp.R

Description

The non-central chi-square approximation is based on a modified Liu method.

Usage

1
lee.pwr(alpha, lambda, delta)

Arguments

alpha

significance level

lambda

vector of mixing coefficients

delta

vector of non-centrality parameters

Value

estimated power

References

Wu,B. and Pankow,J.S. (2016) On sample size and power calculation for variant set-based association tests. /AHG/, 80(2), 136-143.

Wu,B. and Pankow,J.S. (2017) On computing the tail probability of non-negative definite quadratic forms in central normal variables. tech rep.

Lee, S., Wu, M. C., and Lin, X. (2012) Optimal tests for rare variant effects in sequencing association studies. Biostatistics, 13, 762-775.


baolinwu/KATSP documentation built on May 29, 2019, 12:04 p.m.