KATpval: Compute the tail probability of weighted sum of 1-DF...
In baolinwu/MSKAT: Various multi-trait variant-set association test methods
Description
Usage
Arguments
Value
References
Description
Use Davies' method and apply a relative error bound (avoid redundant computations): efficient and accurate.
Usage
1
KATpval(Q.all, lambda, acc = 0.01, lim = 1e+07)
Arguments
Q.all
test statistics
lambda
mixing coefficients
acc
relative error bound
lim
maximum number of integration terms
Value
tail probability
References
Wu,B., Guan,W., Pankow,J.S. (2016) On efficient and accurate calculation of significance p-values for sequence kernel association test of variant set. Annals of human genetics, 80(2), 123-135.
Guo,B. and Wu,B. (2017) Powerful and efficient SNP-set association tests across multiple phenotypes using GWAS summary data. tech rep.
baolinwu/MSKAT documentation built on May 28, 2019, 6:37 p.m.
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Description Usage Arguments Value References
Description
Use Davies' method and apply a relative error bound (avoid redundant computations): efficient and accurate.
Usage
1 | KATpval(Q.all, lambda, acc = 0.01, lim = 1e+07)
|
Arguments
Q.all |
test statistics |
lambda |
mixing coefficients |
acc |
relative error bound |
lim |
maximum number of integration terms |
Value
tail probability
References
Wu,B., Guan,W., Pankow,J.S. (2016) On efficient and accurate calculation of significance p-values for sequence kernel association test of variant set. Annals of human genetics, 80(2), 123-135.
Guo,B. and Wu,B. (2017) Powerful and efficient SNP-set association tests across multiple phenotypes using GWAS summary data. tech rep.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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