loadOvarianDatasets: Function to load ovarian cancer SummarizedExperiment objects...

Description Usage Arguments Value Examples

View source: R/loadOvarianDatasets.R

Description

This function returns ovarian cancer datasets from the hub and a vector of patients from the datasets that are duplicates based on a spearman correlation > 0.98

Usage

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loadOvarianDatasets(
  rescale = FALSE,
  minNumberGenes = 0,
  minNumberEvents = 0,
  minSampleSize = 0,
  keepCommonOnly = FALSE,
  imputeMissing = FALSE,
  removeDuplicates = FALSE
)

Arguments

rescale

apply centering and scaling to the expression sets (default FALSE)

minNumberGenes

an integer specifying to remove expression sets with less genes than this number (default 0)

minNumberEvents

an integer specifying how man survival events must be in the dataset to keep the dataset (default 0)

minSampleSize

an integer specifying the minimum number of patients required in a summarizedExperiment (default 0)

keepCommonOnly

remove entrezIDs not common to all datasets (default FALSE)

imputeMissing

remove patients from datasets with missing expression values

removeDuplicates

remove patients with a Spearman correlation greater than or equal to 0.98 with other patient expression profiles (default TRUE)

Value

a list with 2 elements. The First element named summarizedExperiments contains the datasets. The second element named duplicates contains a vector with patient IDs for the duplicate patients (those with Spearman correlation greater than or equal to 0.98 with other patient expression profiles).

Examples

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experimentsAndDups = loadOvarianDatasets()

bhklab/MetaGxOvarian documentation built on Aug. 14, 2021, 1:59 p.m.