gbm.example: Glioblastoma (GBM) Example Dataset

Description Usage Format

Description

Object containing all the data needed to run the example code for MOMA

Usage

1

Format

An object with 9 different sets of GBM data needed to run the MOMA analysis

vipermat

matrix of viper scores with samples in columns and regulators across the rows

cindy

list of regulators, each with a set of modulators and p values representing their CINDY inferred association

preppi

list of regulators, each with a set of potential binding partners and PREPPi inferred p values for probability of binding

rawsnp

matrix of samples and genes with potential mutations. 0 for no mutation, 1 for presence of some non-silent mutation

rawcnv

matrix of samples and genes with copy number variant scores calculated by GISTIC

fusions

matrix of samples and fusion genes. 0 for no fusion, 1 for presence of fusion

gene.loc.mapping

dataframe with 4 columns, Gene Symbol, Locus ID, Cytoband location, Entrez ID. Used for mapping amplifications and deletions between gene and location

clinical

dataframe of clinical annotations, taken directly from TCGA

fCNV

vector of gene names that have functional CNV mutations

mutSig

blacklist of genes to not use in the DIGGIT analysis


califano-lab/moma.gbmexample documentation built on April 4, 2020, 12:18 a.m.