seizures: Seizures data
In carrascojalmar/MNB: Diagnostic Tools for a Multivariate Negative Binomial Model

seizures

R Documentation

Seizures data

Description

The data set described in Diggle et.al (2013) refers to an experiment in which 59 epileptic patients were randomly assigned to one of two treatment groups: treatment (progabide drug) and placebo groups. The number of seizures experienced by each patient during the baseline period (week eight) and the four consecutive periods (every two weeks) was recorded. The main goal of this application is to analyze the drug effect with respect to the placebo. Two dummies covariates are considered in this study; Group which assumes values equal to 1 if the patient belongs to treatment group and 0 otherwise, and Period which assumes values equal to 1 if the number of seizures are recorded during the treatment and 0 if are measured in the baseline period. It is taking into account the Time covariate which represents the number of weeks required for the counting of seizures in each patient of the placebo and treatment groups.

Usage

data(seizures)

Format

This data frame contains the following columns:

Y: The number epileptic seizure.
trt: Treatment: binary indicators for the prograbide and placebo groups.
period: binary indicator for the baseline period.
week: number od weeks
ind: Indicator on the ith patient.

References

Diggle, P. J., Liang, K. Y., and Zeger, S. L. (2013). Analysis of Longitudinal Data. Oxford University Press, N.Y., 2 edition.
Fabio, L. C., Villegas, C., Carrasco, J. M. F., and de Castro, M. (2021). D Diagnostic tools for a multivariate negative binomial model for fitting correlated data with overdispersion. Communications in Statistics - Theory and Methods. https://doi.org/10.1080/03610926.2021.1939380.