joinNetworks: Join multiple networks around a target node ID

In ccb-hms/BioPlexAnalysis: Applications and downstream analysis of BioPlex PPI data

Join multiple networks around a target node ID

Description

This function joins multiple networks and resticts the joined network to interactions involving a target node ID of interest

Usage

joinNetworks(id, network, intA.col = "SymbolA", intB.col = "SymbolB")

Arguments

id	character. A gene or protein ID around which a joined network should be constructed.
network	list. Each element of the list is a data.frame representing a network. That means each row of a data.frame represents an interaction.
intA.col	character. Name of the column that stores the ID of the first interactor in each data.frame of argument network.
intB.col	character. Name of the column that stores the ID of the second interactor in each data.frame of argument network.

Value

A data.frame containing the joined network.

Examples

 library(BioPlex)
 bp.293t <- BioPlex::getBioPlex(cell.line = "293T", version = "3.0")
 bp.hct <- BioPlex::getBioPlex(cell.line = "HCT116", version = "1.0")
 netl <- list(HEK = bp.293t, HCT = bp.hct)

 jnet <- joinNetworks(id = "CDH2", network = netl)

ccb-hms/BioPlexAnalysis documentation built on Jan. 29, 2023, 6:55 p.m.