R/ICBioMark.R

#' ICBioMark: A package for cost-effective design of gene panels to predict
#' exome-wide biomarkers.
#'
#' @description This package implements the methodology proposed in
#' 'Data-driven design of targeted gene panels for estimating immunotherapy biomarkers',
#' (Bradley and Cannings, 2021, preprint). It allows the user to fit generative models of
#' mutation from an annotated mutation dataset, and then further to produce tunable linear
#' estimators of exome-wide biomarkers. It also contains functions to simulate mutation
#' annotated format (MAF) data, as well as to analyse the output and performance of models.

#' @docType package
#' @name ICBioMark
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cobrbra/ICBioMark documentation built on May 4, 2023, 2:16 a.m.