This function wraps enrichGeneList to call Enrichr to perform functional enrichment tests on the provided gene lists, for the databases specified in the databases argument. Separate analyses are run on upregulated and downregulated genes, the returned results are rbind'ed. Databases are specified as seen in the web interface, with underscores for spaces (e.g. "WikiPathways_2016", "KEGG_2016", "GO_Biological_Process"). See http://amp.pharm.mssm.edu/Enrichr/#stats for more databases.
1 2 | enrichFullGeneList(up.genes, dn.genes, databases = "KEGG_2016",
fdr.cutoff = 0.1)
|
up.genes |
a list of up-regulated gene symbols |
dn.genes |
a list of down-regulated gene symbols |
databases |
a character vector of Enrichr-fronted databases. Default: KEGG_2016 |
fdr.cutoff |
An FDR (adjusted p-value) threshold by which to limit the list of enriched pathways. Default = 0.1 |
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