enrichFullGeneList: Perform functional enrichment on a pair of "up"- and "down"-...

Description Usage Arguments

View source: R/api_wrapper.R

Description

This function wraps enrichGeneList to call Enrichr to perform functional enrichment tests on the provided gene lists, for the databases specified in the databases argument. Separate analyses are run on upregulated and downregulated genes, the returned results are rbind'ed. Databases are specified as seen in the web interface, with underscores for spaces (e.g. "WikiPathways_2016", "KEGG_2016", "GO_Biological_Process"). See http://amp.pharm.mssm.edu/Enrichr/#stats for more databases.

Usage

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enrichFullGeneList(up.genes, dn.genes, databases = "KEGG_2016",
  fdr.cutoff = 0.1)

Arguments

up.genes

a list of up-regulated gene symbols

dn.genes

a list of down-regulated gene symbols

databases

a character vector of Enrichr-fronted databases. Default: KEGG_2016

fdr.cutoff

An FDR (adjusted p-value) threshold by which to limit the list of enriched pathways. Default = 0.1


compbiomed/enrichR documentation built on May 13, 2019, 9:55 p.m.