groupTestByGeneOntology: Run DISCOVER group-wise tests on gene sets defined by gene...

Description Usage Arguments

Description

This implements the discover group wise tests of exclusivity, coverage and impurity "https://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-1114-x". Automatically implements a the Benjamini-Hochberg multiple testing correction.

Usage

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groupTestByGeneOntology(events, dictionary = NULL, go.type = "bp",
  group.test.type = "exclusivity")

Arguments

events

Can either be a discover matrix that results from running the discover.pairwise.test() or an indicator matrix. If it is an indicator matrix, the function will run the discover test, but this will significantly increase execution time.

dictionary

If a dictionary object (makeDictionary) is not supplied this function will automatically generate one, though this increases execution time.

go.type

Character. Can be "bp","cc" or "mf" for biological process, cellular component, or molecular function respectively. Defaults to "bp"

group.test.type

The type of group test to be employed: "exclusivity", "coverage" or "impurity"


connorH982/driverAnalytics documentation built on May 23, 2019, 8:55 a.m.