signatureGenes: Signature Genes

In d3b-center/medullo-classifier-package: Medulloblastoma Classifier

Signature Genes

Description

Function to calculate gene ratio matrix

Usage

signatureGenes(exprs = NULL, signatureProbes = NULL)

Arguments

exprs	expression matrix in which the rows contains the HUGO/HGNC gene symbols and the columns are the samples identifiers. The entries inside the matrix are the respective gene expression values. (see details section for more info)
signatureProbes	character vector of gene signatures

Details

Function for determining the gene ratio matrix. The function expects an expression matrix as the only necessary input parameter. The expression matrix must be one of the following formats: (1) FPKM (2) TPM (3)quantile normalized data (4) microarray data.

The expected output is a matrix data frame in which the row names are the gene ratio symbols and the column names are the sample identifiers.

Author(s)

Pichai Raman

Komal S. Rathi

Sherjeel Arif

Examples

# Load example data containing expression matrix
data(exprs_109401)

# use function
geneRatioOut_109401 <- signatureGenes(exprs_109401)

# View gene ratio matrix
head(geneRatioOut_109401[1:5])

d3b-center/medullo-classifier-package documentation built on June 28, 2023, 8:16 p.m.