oranges: ORANGES: Over-Representation ANalysis for Gene Expression...

Description Usage Arguments Value

Description

oranges returns the enrichment of pathway sets given a query gene signature based on Fisher's exact test. Currently this function is built around enrichment of human pathway sets, but ora function can be generalized to fit different organisms of interest provided a pathway matrix is provided.

Usage

1
oranges(query_entrez, universe_entrez)

Arguments

universe_entrez

Full EntrezID set where the query set comes from (usually the full set of RNA-seq or microarray genes characterized in the transcriptomics platform)

query_set

Gene signature of interest, as EntrezIDs

universe_symbols

Gene symbols for the entire set of genes in universe

Value

A tibble.


diogocamacho/oranges documentation built on June 6, 2019, 11:52 p.m.