PVCA: A function for principal variance component analysis

Description Usage Arguments Value

Description

The function is written based on the 'pvcaBatchAssess' function of the PVCA R package and slightly changed to make it more efficient and flexible for sequencing read counts data. (http://watson.nci.nih.gov/bioc_mirror/packages/release/bioc/manuals/pvca/man/pvca.pdf)

Usage

1
PVCA(counts, meta, threshold, inter)

Arguments

counts

The Normalized(e.g. TMM)/ log-transformed reads count matrix from sequencing data (row:gene/feature, col:sample)

meta

The Meta data matrix containing predictor variables (row:sample, col:predictor)

threshold

The proportion of the variation in read counts explained by top k PCs. This value determines the number of top PCs to be used in pvca.

inter

TRUE/FALSE - include/do not include pairwise interactions of predictors

Value

std.prop.val The vector of proportions of variation explained by each predictor.


dleelab/pvca documentation built on May 15, 2019, 9:15 a.m.