snipe: Run SNIPE Analysis

Description Usage Arguments Value Author(s) See Also Examples

Description

Run SNIPE analysis on a pair of data sets. Can split the calculation load amongst multiple cores on a single machine.

Usage

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snipe(treatment, control, species, njobs = 1, nperms.per.job = 1000000, dbpath = "snipe_maps")

Arguments

treatment

Path to the file containing the treatment data.

control

Path to the file containing the control data.

species

NCBI Taxon ID for the species the data applies to.

njobs

Number of jobs to divide the work in to.

nperms.per.job

Number of permutations per job to run.

dbpath

Pathway to databases including STRING and ID maps.

Value

Returns a table containing the following fields: Ensembl Protein ID (from STRING), Official Gene Symbol, Protein Description, Observed Spectral Count in the treatment, Observed spectral count in the control, Observed Chi score, uncorrected p-value, and multiple test corrected p-value.

Author(s)

David Nusinow dnusinow@partners.org

See Also

download.missing.maps

Examples

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data("Tooth_Proteins")
## Not run: snipe.out <- snipe(treatment = tooth_germ, control= oral_tissue, njobs = 5, nperms.per.job = 200000, species = 10090, dbpath = "~/nethome/data/snipe_maps")

dnusinow/snipeR documentation built on May 15, 2019, 9:40 a.m.