Description Usage Arguments Value Examples
View source: R/operating_characteristics.R
Calculate the bias.
1 | mtd_bias(mtd_estimate, true_mtd)
|
mtd_estimate |
a numerical vector of the MTD estimates. |
true_mtd |
a numerical value of the true Maximum Tolerable Dose. |
Bias of the MTD estimates.
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 | ## Not run:
DLT <- 0
dose <- 20
step_zero <- ewoc_d1classical(DLT ~ dose, type = 'discrete',
theta = 0.33, alpha = 0.25,
min_dose = 0, max_dose = 100,
dose_set = seq(0, 100, 20),
rho_prior = matrix(1, ncol = 2, nrow = 1),
mtd_prior = matrix(1, ncol = 2, nrow = 1),
rounding = "nearest")
response_sim <- response_d1classical(rho = 0.05, mtd = 20, theta = 0.33,
min_dose = 10, max_dose = 50)
sim <- ewoc_simulation(step_zero = step_zero,
n_sim = 2, sample_size = 30,
alpha_strategy = "increasing",
response_sim = response_sim,
ncores = 2)
mtd_bias(sim$mtd_sim, true_mtd = 20)
## End(Not run)
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