gLRTH: The Function for the Likelihood Ratio Test for Genome-Wide...

Description Usage Arguments Value Author(s) References Examples

Description

The Function for the Likelihood Ratio Test for Genome-Wide Association under Genetic Heterogeneity with genotype frequencies as input values

Usage

1
gLRTH(n0, n1, n2, m0, m1, m2)

Arguments

n0

AA genotype frequency in case

n1

Aa genotype frequency in case

n2

aa genotype frequency in case

m0

AA genotype frequency in control

m1

Aa genotype frequency in control

m2

aa genotype frequency in control

Value

The test statistic and asymptotic p-value for the likelihood ratio test under genetic heterogeneity

Author(s)

Xiaoxia Han and Yongzhao Shao

References

Qian M., Shao Y. (2013) A Likelihood Ratio Test for Genome-Wide Association under Genetic Heterogeneity. Annals of Human Genetics, 77(2): 174-182.

Examples

1
gLRTH(n0=2940, n1=738, n2=53, m0=3601, m1=1173, m2=117)

echohan/gLRTH documentation built on May 15, 2019, 7:51 p.m.