ksea_batchKinases: Batch KSEA for all kinase regulons

Description Usage Arguments Details Value Author(s)

Description

Runs KSEA in batch for all Kinase-Substrates

Usage

1
ksea_batchKinases(ranking, logvalues, regulons, trial = 1000)

Arguments

ranking

vector with all quantified positions

logvalues

vector with all quantifications

regulons

list containing vectors with substrates of each kinase. Substrates should be encoded with the same id as the ranking vector.

trial

Number of permutations used for the empirical p-value generation.

Details

This functions allows to run the KSEA in a given dataset for all provided kinases. The function makes use of all available cores in the computer (using parallel) package.

Value

A vector of p-values containing all KSEA p-values for all

Author(s)

David Ochoa


evocellnet/ksea documentation built on May 16, 2019, 9:40 a.m.