strategy1: MR Strategy 1

In explodecomputer/tryx: MR-TRYX (treasure your exceptions)

Description

How to choose the result for a set of different MR analysies? Simple strategy: Use Wald ratio if only one SNP Use IVW if more than one SNP and heterogeneity is low Use weighted mode if more than some minimum number of SNPs and heterogeneity is high

Usage

strategy1(dat, het_threshold = 0.05, ivw_max_snp = 1)

Arguments

dat	Output from harmonise_data function
het_threshold	The p-value threshold for Cochran's Q - if lower than this threshold then run weighted mode. Default p = 0.05
ivw_max_snp	Maximum SNPs to allow IVW result even if heterogeneity is high. Default = 1

explodecomputer/tryx documentation built on July 26, 2020, 2:45 p.m.