Fits a multivariate linear mixed effects model that uses a polygenic term, after Zhou & Stephens (2014) (<https://www.nature.com/articles/nmeth.2848>). Of particular interest is the estimation of variance components with restricted maximum likelihood (REML) methods. Genome-wide efficient mixed-model association (GEMMA), as implemented in the package 'gemma2', uses an expectation-maximization algorithm for variance components inference for use in quantitative trait locus studies.
Package details |
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Maintainer | |
License | MIT + file LICENSE |
Version | 0.1.3 |
URL | https://github.com/fboehm/gemma2 |
Package repository | View on GitHub |
Installation |
Install the latest version of this package by entering the following in R:
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