fboehm/limmbo2: Covariance Matrices Estimation for Multivariate Linear Mixed Effects Models in Genetics Studies

limmbo2 is a R wrapper for the python module limmbo. limmbo performs covariance estimation for the multivariate linear mixed effects model, vec(Y) = X vec(B) + vec(G) + vec(E), where E and G are both matrix-variate normally distributed. The method relies on combination of multiple covariance matrix estimates from bootstrapped subsets of the phenotypes. Details are in a preprint at https://www.biorxiv.org/content/early/2018/01/30/255497.

install.packages("remotes")
remotes::install_github("fboehm/limmbo2")