GBDCorTest: Gene-based gene-gene interaction via distance correlation...

Description Usage Arguments Value References

Description

GBDCorTest computes the p-value of the GBDcor test based on the distance correlation coefficient. See Guo et al, 2018 for more details.

Usage

1
GBDCorTest(X1, X2, Y, Y0)

Arguments

X1

a n x p1 matrix of genotypes (coded as 0/1/2)

X2

a n x p2 matrix of genotypes (coded as 0/1/2)

Y

a vector of length n containing the values of the binary phenotype (0/1)

Y0

a matrix containing permutations of the phenotype Y in its columns

Value

The p-value of the GBDcor test.

References

Guo, Y., Wu, C., Guo, M., Liu, X., & Keinan, A. (2018). Gene-Based Nonparametric Testing of Interactions Using Distance Correlation Coefficient in Case-Control Association Studies. Genes, 9(12), 608.


fhebert/GeneGeneInteractions2 documentation built on May 19, 2019, 12:36 a.m.