Description Usage Arguments Value Author(s)
Computes the conditional type I error rate of a pre-planned t-test (using inverse normal combination of stage-wise t-tests) in a two-stage parallel group adaptive design. We condition on the observed first stage data and treatment assignment as well as the pre-planned second stage sample size.
1 |
x1 |
First stage observations |
g1 |
First stage treatment assignments (1 for control, -1 for treatment) |
n |
Preplanned overal sample size |
alpha |
pre-fixed significance level |
numeric value of the conditional error rate
Florian Klinglmueller
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