README.md

Matrix eQTL: Ultra Fast eQTL Analysis via Large Matrix Operations

Matrix eQTL is designed for fast eQTL analysis on large datasets. Matrix eQTL can test for association between genotype and gene expression using linear regression with either additive or ANOVA genotype effects. The models can include covariates to account for factors as population stratification, gender, and clinical variables. It also supports models with heteroscedastic and/or correlated errors, false discovery rate estimation and separate treatment of local (cis) and distant (trans) eQTLs. For more details see Shabalin (2012).

Installation

Install CRAN Version

To install the CRAN version of MatrixEQTL, run

install.packages("MatrixEQTL")

Install GitHub Version

To install MatrixEQTL directly from GitHub, run

if(!requireNamespace("devtools", quietly = TRUE))
    install.packages("devtools")
devtools::install_github("andreyshabalin/MatrixEQTL")


foster-gabe/MatrixEQTL documentation built on July 3, 2020, 12:03 a.m.