exampleDepMat: Example dependency matrix data object

In francescojm/ADAM: Adaptive Daisy Model

Description

A binary matrix summarising the fitness effect status (1 = cellular fitness reduced upon gene inactivation via CRISPR-Cas9 targeting) of all the genes (at a genome scale) across 32 human colorectal cancer cell lines, derived from [1].

Usage

data("exampleDepMat")

Format

The format is: num [1:17995, 1:32] 0 0 0 0 0 0 0 0 0 0 ... - attr(*, "dimnames")=List of 2 ..$ : chr [1:17995] "A1BG" "A1CF" "A2M" "A2ML1" ... ..$ : chr [1:32] "Cell_line_1" "Cell_line_2" "Cell_line_3" "Cell_line_4" ...

References

[1] Behan FM & Iorio F & Picco G et al., Prioritisation of cancer therapeutic targets using CRISPR-Cas9 screens. Nature, In press.

Examples

data(exampleDepMat)
head(exampleDepMat)

francescojm/ADAM documentation built on May 11, 2019, 8:21 p.m.