scripts/README.md

In gavinha/TitanCNA: Subclonal copy number and LOH prediction from whole genome sequencing of tumours

Scripts and Pipeline code for TitanCNA analysis

Contents

• Standard Whole Genome/Exome Sequencing Analysis
• 10X Genomics Whole Genome Sequencing Analysis

1. Standard Whole Genome/Exome Sequencing Analysis

a. We provide a Snakemake implementation of the pipeline to perform TITAN analysis starting from BAM files to TitanCNA results. Please see snakemake/ for more details.

b. R scripts for running TitanCNA analysis The R_scripts directory contains the actual R script to run the (R component of the) TitanCNA analysis as well as an R script to select the optimal solution. While the Snakemake pipeline will make use of R script within R_scripts, you can learn about more details of the R script here R_scripts/.

2. 10X Genomics Whole Genome Sequencing Analysis

The Snakemake workflow is in another Git repo: https://github.com/gavinha/TitanCNA_10X_snakemake

gavinha/TitanCNA documentation built on April 22, 2021, 9:38 a.m.