helper_minmax: Helper function for minmax method.

In gokmenzararsiz/dtComb: Statistical Combination of Diagnostic Tests

Helper function for minmax method.

Description

The helper_minmax function estimates optimized value of given biomarkers for the minmax method.

Usage

helper_minmax(lambda, neg.set, pos.set)

Arguments

lambda	a numeric parameter that will be estimated in minmax method for the combination score
neg.set	a numeric data frame that contains the observations with negative status
pos.set	a numeric data frame that contains the observations with positive status

Value

A numeric value for the estimated optimized value

Author(s)

Serra Ilayda Yerlitas, Serra Bersan Gengec, Necla Kochan, Gozde Erturk Zararsiz, Selcuk Korkmaz, Gokmen Zararsiz

Examples

# call data
data(laparotomy)

# define the function parameters
markers <- cbind(laparotomy$ddimer, laparotomy$log_leukocyte)
status <- factor(laparotomy$group, levels = c("not_needed", "needed"))

neg.set <- markers[status == levels(status)[1], ]
pos.set <- markers[status == levels(status)[2], ]

lambda <- 0.5

stat <- helper_minmax(lambda, neg.set = neg.set, pos.set = pos.set)

gokmenzararsiz/dtComb documentation built on April 17, 2025, 12:50 p.m.