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The data are from a randomized trial comparing two oral treatments for toenail dermatophyte onychomycosis infection, see De Backer et al. (1996). Participants were evaluated at baseline (month 0) and at 1, 2, 3, 6, 9 and 12 months. The response variable is the unaffected nail length expressed in mm.
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A data frame with 1854 rows and 4 variables:
Unique subject identifier
Treatment group identifier
month
Unaffected Nail Length (UNL) in millimeters, measured from the nail bed to the infected part of the nail.
Most recently, Mian and Hasan (2012) and Mahabadi (2014) have analyzed the toenail data.
Additional information is available at
http://www.aliquote.org/articles/tech/MDLD/README.html
De Backer, M., De Keyser, P., De Vroey, C. and Lesaffre, E. (1996). A 12-week treatment for dermatophyte toe onychomycosis: terbinafine 250mg/day vs. itraconazole 200mg/day–a double-blind comparative trial. British Journal of Dermatology, 134, 16-17. http://www.jaad.org/article/S0190-9622(98)70486-4/abstract
Mian, R. I. and Hasan, M. T. (2012). Two-part pattern-mixture model for longitudinal incom- plete semi-continuous toenail data. International Journal of Statistics in Medical Research, 1(2):120–127.
Mahabadi, S. E. (2014). A bayesian shared parameter model for incomplete semicontinuous longitudinal data: An application to toenail dermatophyte onychomycosis study. Journal of Statistical Theory and Applications, 13(4):317–332.
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