Description Usage Arguments Details Author(s) References See Also
Plots of the operating characteristics obtained from a CRM simulation.
1 2 |
x |
An object of class "bcrm.sim", as returned by |
trajectories |
Should a summary plot of the trajectories of administered dose levels be plotted? Defaults to FALSE. |
file |
File name where the operating characteristic plot is stored, in a pdf format. |
threep3 |
Should operating characteristics of a standard 3+3 rule-based design be plotted alongside the |
... |
Further arguments passed to or from other methods |
This function plots the sample size distribution (if variable), the experimentation distribution, the recommended dose distribution and the percentage of subjects who experience the toxicity outcome (dose-limiting toxicity).
If trajectories = TRUE
then summary statistics of administered dose levels for each patient are plotted instead.
If threep3 = TRUE
then the operating characteristics of the standard 3+3 design are plotted alongside those of the bcrm
design (see threep3
for more details).
Michael Sweeting mjs212@medschl.cam.ac.uk (University of Cambridge, UK)
Sweeting M., Mander A., Sabin T. bcrm: Bayesian Continual Reassessment Method Designs for Phase I Dose-Finding Trials. Journal of Statistical Software (2013) 54: 1–26. http://www.jstatsoft.org/article/view/v054i13
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