RMTLd_test: Comparing restricted mean survival time

In hongji-wu/crRMTL: Restricted mean time lost (RMTL) analysis under competing risks

Description

Performs two-sample comparisons using the restricted mean time lost(RMTL) as a summary measure of the cumulative incidence function under competing risks

Usage

RMTLd_test(time, status, group, alpha = 0.05, digits = 3, tau = NULL)

Arguments

time	The follow-up time for right censored data.
status	The status indicator, 1 = event of interest, 2 = competing event and 0 = right censored.
group	The group indicator for comparison. The elements of this vector take either 1 or 0. Normally, 0 = control group, 1 = active treatment group.
alpha	The default is 0.05. (1-alpha) confidence intervals are reported.
digits	The decimal places settings, digitis = 3 are set by default.
tau	A scaler value to specify the truncation time point for the RMST calculation. The default is the minimum of the maximum follow-up time of two groups

Value

an object of class RMTLd_test.

tau	the truncation time used in the analyses
Note	a note regarding the specification of the truncation time(tau), the default tau will be reported if tau was not specified.
RMTL	RMTL results in two groups, including RMTL of event 1 and event 2, and corresponding variance and CI in group 0 and 1
Test.event1	Three kinds of effect size between groups of event 1, including Cause-specific Hazard Ratios(CHR), Subdistributional Hazard Ratio(SHR) and RMTLd, and corresponding confidence intervals. Meanwhile, the Z-statistics and P-value are estimated via log-rank test(CHR), Gray's test(SHR) and RMTLd test(RMTLd)
Test.event2	Three kinds of effect size between groups of event 2, including Cause-specific Hazard Ratios(CHR), Subdistributional Hazard Ratio(SHR) and RMTLd, and corresponding confidence intervals.

Meanwhile, the Z-statistics and P-value are estimated via log-rank test(CHR), Gray's test(SHR) and RMTLd test(RMTLd)

Examples

library(crRMTL)
data(simdata)
# The time point is set as the minimum of the maximum follow-up time of two groups when tau = NULL.
RMTLd_test(simdata$time, simdata$status, simdata$group, alpha = 0.05, digits = 3, tau = NULL)
# The time point is set as tau = 3.
RMTLd_test(simdata$time, simdata$status, simdata$group, alpha = 0.05, digits = 3, tau = 3)

hongji-wu/crRMTL documentation built on Jan. 16, 2022, 12:37 a.m.